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R. Soc. Interface 7: 863–871. -H. & Takeuchi, S. (2007). A trap-and-release integrated microfluidic system for dynamic microarray applications, Proc. Natl. Acad. Sci. USA 104: 1146–1151. -H. & Takeuchi, S. (2008). Dynamic microarray system with gentle retrieval mechanism for cell-encapsulating hydrogel beads, Lab Chip 8: 259–266. 1039/B714573J Theberge, A. , Hollfelder, F. & Huck, W. T. S. (2010). Microdroplets in microfluidics: An evolving platform for discoveries in chemistry and biology, Angew.

Thermocapillary drift of an air bubble in a horizontal Hele-Shaw cell, Fluid Dyn. 19: 393–398. , Goddard, N. L. & Libchaber, A. (2003). Exponential DNA replication by laminar convection, Phys. Rev. Lett. 91: 158103. 158103 Braun, D. & Libchaber, A. (2002). Trapping of DNA by thermophoretic depletion and convection, Phys. Rev. Lett. 89: 188103. 188103 Braun, D. & Libchaber, A. (2004). Thermal force approach to molecular evolution, Phys. Biol. 1: P1–P8. , Troian, S. M. & Carles, P. (1990). Fingering instability of thin spreading films driven by temperature gradients, Nature 346: 824–826.

It can easily be observed that pushing the focused stream away from the microchannel axis grows with an increase of the ratio of side streams. Another aspect of deformation of the focused stream is the dependence of stream curvature on flow conditions. Figure 13 shows the dependence of curvature c of the focused stream on pushing the stream away from the channel axis z. 40 Advances in Microfluidics Fig. 13. Deformation of the focused stream as a function of pushing it away from the channel axis.

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