Download Antimicrobial Drug Resistance: Clinical and Epidemiological by Lesley McGee, Keith P. Klugman (auth.), Douglas L. Mayers MD PDF

By Lesley McGee, Keith P. Klugman (auth.), Douglas L. Mayers MD (eds.)

The volumes incorporated in Antimicrobial Drug Resistance signify the 1st accomplished, multidisciplinary reference protecting the realm of antimicrobial drug resistance in micro organism, fungi, viruses, and parasites from uncomplicated technological know-how, medical, and epidemiological perspectives.

The first quantity, Antimicrobial Drug Resistance, Mechanisms of Drug Resistance, is devoted to the organic foundation of drug resistance and potent avenues for drug improvement. With the emergence of extra drug-resistant traces, the method of facing the drug resistance challenge needs to contain the study of alternative facets of the mechanisms of bacterial resistance and the dissemination of resistance genes in addition to learn using new genomic details. those methods will enable the layout of novel options to strengthen new antibiotics and guard the effectiveness of at present on hand ones.

The moment quantity, Antimicrobial Drug Resistance, medical and Epidemiological Aspects, is dedicated to the scientific points of drug resistance. even supposing there's facts that constrained use of a particular antibiotic could be through a reduce in drug resistance to that agent, drug resistance regulate isn't simply completed. hence, the infectious illness healthcare professional calls for enter from the scientific microbiologist and an infection keep watch over expert to make proficient offerings for the potent therapy of varied lines of drug-resistant pathogens in person patients.

This 2-volume set is a vital reference for college kids in microbiology, infectious sickness physicians, clinical scholars, uncomplicated scientists, drug improvement researchers, microbiologists, epidemiologists, and public overall healthiness practitioners.

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Additional info for Antimicrobial Drug Resistance: Clinical and Epidemiological Aspects

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Whatsoever, all this data indicate that penicillin is in vitro as effective as cephalosporins against VGS although ceftriaxone has, in vitro, lower resistance figures than penicillin if the new NCCLS breakpoints are used (43, 44). Imipemen, a carbapenem antibiotic, is in vitro active against VGS (45). e. 5 mg/L (24, 31). However, strains, highly penicillin resistant, can have elevated MICs (1–2 mg/L) (24). , have found that 20% of the VGS blood isolates of neutropenic cancer patients can have imipenem MIC of 1 mg/L or more (31).

Risk factors and response to antibiotic therapy in adults with bacteremic pneumonia caused by penicillin-resistant pneumococci. N Engl J Med 1987;317:18–22 Bryan CS, Talwani R, Stinson MS. Penicillin dosing for pneumococcal pneumonia. Chest 1997;112:1657–1664 Kaplan SL, Mason Jr EO, Barson WJ, et al. Outcome of invasive infections outside the central nervous system caused by Streptococcus pneumoniae isolates nonsusceptible to ceftriazone in children treated with beta-lactam antibiotics. Pediatr Infect Dis J 2001;20:392–396 Pallares R, Capdevila O, Linares J, et al.

The challenge of penicillin-resistant Streptococcus pneumoniae meningitis: current antibiotic therapy in the 1990s. Clin Infect Dis 1997;24(Suppl 2):S213–S221 Chambers H. Methicillin-resistant staphylococci. Clin Microbiol Rev 1988;1:173–186 Deal W, Sanders E. Efficacy of rifampicin in treatment of meningococcal carriers. N Engl J Med 1969;281:641–645 Band J, Fraser D, Ajello G. Prevention of Haemophilus influenzae type b disease. JAMA 1984;251:2381–2386 Doern GV, Brueggemann A, Holley HP Jr, Rauch AM.

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